In Vitro Screening Antifungal Efficacy of Various Essential Oils Against Candida albicans

المجلة: Azerbaijan Medical Journal

سنة النشر: 2022

تاريخ النشر: 2022-08-10

Abstract : Candida albicans is the common fungal pathogen called Candidiasis, is the term used to describe an infection caused by an overgrowth of yeast, causing multi-drug-resistant candidiasis in humans. Essential oils are characterized as important substances in pharmaceutical products for a long time ago. The antifungal effects of various essential oils and plant compounds have been established in contradiction of human pathogenic fungi. The aim of this study is to assess the fungistatic activities for 17 essential oils against Candida albicans species. Essential oils (Castor, Sidr, Neem, Clove, Black pepper, Cress, Calptus, Learners, Turmeric, Lemon, Cypress, Taramira, Peppermint, cinnamon bark, Tea tree, Glycerin, Sesame oil) were used to screening their effects against vaginal Candida albicans. The antifungals efficacy of essential oils was evaluated by the cup plate agar diffusion method on Saboraiud dextrose agar. Screening the best essential oil to be used against vaginal candidiasis indicated that cinnamon bark essential oil which inhibited the tested strains and showed widest a fungistatic activity reached 23 mm, while Clove oil and Cypress oil were produced inhibition halos with diameters of 9 and mm and 12.5 mm, respectively. The findings reported here demonstrate that clove, Cypress and cinnamon bark essential oils detected as effective oils against Candida albicans as a natural compound to have highly efficacious as antifungal agents, this due to the high therapeutic efficiency and low toxicity in the treatment of different fungal infections caused by Candida spp, however, the antifungal and inhibition activity raise another interesting field in researching antifungal therapeutic interventions in both clinical and industrial applications.