The effects lactobacillus crispatus probiotics on proliferation and metastasis of cervical cancer cell line using 3D cell culture A Adnan, E Motevaseli, E Sadroddiny

المجلة: EXECUTIVE EDITOR

سنة النشر: 2018

تاريخ النشر: 2018-07-17

Objective: Probiotics has been tried as an adjuvant therapy for malignant tumors through their abilities to modulate intestinal microbiota, host immune response and gene expression. Further, there are emerging data supporting the role of probiotic lactic acid bacteria in prevention of early stages colon cancer development but data on their effect on advanced colorectal cancer and cervical cancer are limited. Therefore, the aim of this study was to evaluate the impact of lactobacillus crispatus supernatant (LCS) on the human cervical cell lines (HeLa) proliferation and metastasis.

Metastasis of Cervical Cancer Cell Line Affected by Probiotics in Real-time PCR Assay

المجلة: 10.22541/au.171489675.58664168/v1

سنة النشر: 2024

تاريخ النشر: 2024-07-21

: The term "probiotic" refers to live microorganisms that have been linked to advantageous outcomes for the host. Nonetheless, a large body of research suggests that probiotic lactic acid bacteria (LAB) may be helpful in preventing colon cancer in its early stages. However, nothing is known about how probiotic LAB may affect colorectal and cervical cancer in their later phases, particularly with regard to metastasis. The objective of our research

The Effects Lactobacillus Crispatus Probiotics on Proliferation and Metastasis of Cervical Cancer Cell Line using 3D Cell Culture

المجلة: EXECUTIVE EDITOR

سنة النشر: 2018

تاريخ النشر: 2018-11-21

Probiotics has been tried as an adjuvant therapy for malignant tumors through their abilities to modulate intestinal microbiota, host immune response and gene expression. Further, there are emerging data supporting the role of probiotic lactic acid bacteria in prevention of early stages colon cancer development but data on their effect on advanced colorectal cancer and cervical cancer are limited. Therefore, the aim of this study was to evaluate the impact of lactobacillus crispatus supernatant (LCS) on the human cervical cell lines (HeLa) proliferation and metastasis.

Understanding the link between diabetes mellitus and fatty liver disease: A narrative review

المجلة: International Journal of Chemical Studies 2024; 12(4): 40-48

سنة النشر: 2024

تاريخ النشر: 2024-08-26

Non-alcoholic fatty liver disease (NAFLD) is very common in people with type 2 diabetes mellitus (T2DM). This is probably because people with T2DM are often overweight and have trouble using insulin. People with type 1 diabetes (T1DM) can also have NAFLD, but it is important to tell the difference between the two. Glycogen hepatopathy is more common in people with T1DM and can cause hepatomegaly and problems with liver function. People with diabetes who are overweight or fat can avoid or treat NAFLD by losing weight through diet and exercise. People with T2DM who have NAFLD can also get better with bariatric surgery. New weight loss drugs should also be studied to see how they affect the growth and spread of NAFLD. A few studies show that statins and some drugs used to treat T2DM (such as TZDs, GLP-1 analogs, and DPP-4) inhibitors) may help diabetes people avoid or treat NAFLD. Type 2 Diabetes Mellitus (T2DM) and Nonalcoholic Fatty Liver Disease (NAFLD) are spreading quickly around the world. Soon, they will be found in every country. There is a link between them because of metabolic risk factors like being overweight, having insulin resistance (IR), and living a poor life. It increases the chance of both liver and heart problems. Some patients feel bad about using the term "NAFLD," but not all of them do. Soon, a more useful one will be released. Medical treatments can work on both diseases at the same time because their main pathophysiological process is the same. Lifestyle changes, drug choices (as more molecules designed for treating T2DM may also help with NAFLD), and surgery are some of the strategies that can be used. This review is mostly about how NAFLD and T2DM can happen together, such as how to use the right words, how common it is, and how many diabetics die from it. To sum up, we've talked about the main pathophysiological processes, the risk stratification method for NAFLD and nonalcoholic steatohepatitis (NASH), and the tools that are used to measure fibrosis. Last but not least, we looked at the different ways that NAFLD linked to T2DM can be treated right now.